DESCRIPTION Rapact 10mg belongs to the anti-neoplastic agent; it comes under mTOR kinase inhibitor (single transduction inhibitor). Rapact 10mg is an immunosuppressive macrolide. USED FOR Breast cancer Patient who fails to respond to the tablet letrozole or anastrozole therapy would be treated with Rapact. Rapact 10mg is used in an advanced stage of breast cancer. Neuroendocrine tumors Rapact 10mg involved in the treatment of some neuroendocrine tumors like pancreatic, gastrointestinal or lung cancer. Renal cell cancer patient treating with Rapact 10mg after the failure of treatment with Sunitinib or Sorafenib. Rapact 10mg also used in the condition of; Heart, liver, kidney transplantation Waldenström macroglobulinemia Other carcinoid tumors. MECHANISM OF ACTION Rapact is the prohibition of mammalian target of rapamycin (mTOR), a serine-threonine kinase. Rapact bind with intercellular protein (FKBP-12), leads to inhibitory complex formation with mTOR complex