BORTEZOMIB INJECTION Bortezomib belongs to anti-cancer medicine, which is available in the form of lyophilized powder. Bortezomib is a first beneficial proteasome inhibitor; proteasome is a cellular structure that breaks the proteins. INDICATION Bortezomib is majorly used to treat Multiple myeloma. Mantle cell lymphoma. DOSAGE AND ADMINISTRATION Generally, Bortezomib is in lyophilized powder form; which is reconstituted by using 0.9% sodium chloride (NS) Bortezomib should be reconstituted in 3.5ml NS The route of administration is IV bolus Intrathecal not use for administration. IN ADULTS MANTLE CELL LYMPHOMA The usual dose of Bortezomib for untreated mantle cell lymphoma is; 1.3mg/m2 of Bortezomib administered as IV bolus given as two times weekly by combining with rituximab, cyclophosphamide, doxorubicin, and tablet prednisolone for two weeks (the day I, IV, VIII & XI) followed by...