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Cabozantinib tablets online | Blueberry Pharmaceuticals

CABOZANTINIB

It belongs to the targeted therapy drug used to cure medullary thyroid cancer and kidney cancer that has spread. Cabozantinib label includes a black box warning of gastrointestinal perforations, fistulas, and haemorrhage. Cabozantinib is a prescription drug which is used under the supervision of doctors

INDICATION

Cabozantinib is indicated for the treatment of metastatic medullary thyroid cancer and for the treatment of patients having advanced renal cell carcinoma (RCC) who have to get before anti-angiogenic therapy.

MECHANISM OF ACTION

Cabozantinib belongs to a type of targeted therapy drug known as a tyrosine kinase inhibitor. It acts by inhibiting the signals inner cancer cells which made them grow and divide. This may help to block or reduced the growth of cancer. It can also prohibit new blood vessels growing in cancer. Cancer cells require to make new blood vessels so they can develop and spread.

DOSAGE AND ADMINISTRATION

The prescribed dose of Cabozantinib is 60 mg.
Administration Cabozantinib is without food.
Advise the patients not to eat for at least 2 hours before and 1 hour after taking Cabozantinib. Follow the treatment until the patient no longer experiences clinical benefit or experiences unacceptable toxicity.
Swallow Cabozantinib tablets whole. Do not crush Cabozantinib tablets.

SIDE EFFECTS

• Haemorrhage
• GI perforations and fistulas
• Thrombotic events
• Hypertension and hypertensive crisis
• Diarrhea
• Palmar-plantar erythrodysesthesia
• Reversible posterior leukoencephalopathy syndrome

PRECAUTIONS

Check the patients for symptoms of perforations and fistulas, contain abscess. stop Cabozantinib in patients who experience a perforation or a fistula. Avoid administer Cabozantinib to patients with a present history of haemorrhage or haemoptysis. Stop the Cabozantinib in patients who develop an acute myocardial infarction, cerebral infarction, or any other clinically significant arterial thromboembolic complication.

DRUG-DRUG INTERACTION

While interaction with a strong CYP3A4 inhibitor will increase the single dose plasma Cabozantinib exposure by 38%. While interaction with strong CYP3A4 inducers will decrease the single dose plasma Cabozantinib exposure by 77%. The combination with MRP2 inhibitors may increase the exposure to Cabozantinib

CONTRAINDICATIONS

Cabozantinib has contraindicated patients having a hypersensitivity reaction to the active substance or its excipients.

STORAGE

Store the drug at below 25°C Keep away from the children resistances

MISSED DOSE

If the patient vomits after taking a dose of Cabozantinib or missed to take a dose, they should not take an extra dose, but to take the next dose at the regular time, skip the missed dose. Do not take the missed dose within 12 hours of the next dose.

FOR MORE INFORMATION:


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info@blueberrypharma.com

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