Evertor 10 mg | Everolimus | blueberry pharmaceuticals

EVERTOR 10MG

Evertor 10mg belongs to the anti-neoplastic agent; it comes under mTOR kinase inhibitor (single transduction inhibitor). Evertor is an immunosuppressive macrolide.

EVERTOR USED FOR

Breast cancer
Patient who fails to respond to the tablet letrozole or anastrozole therapy would be treated with Evertor. Evertor is used in an advanced stage of breast cancer.

Neuroendocrine tumors
Evertor involved in the treatment of some neuroendocrine tumors like pancreatic, gastrointestinal or lung cancer.

Renal cell cancer
Patient treating with Evertor after the failure of treatment with Sunitinib or Sorafenib.

Evertor also used in the condition of Heart, liver, kidney transplantation, Waldenstrom macroglobulinemia, Other carcinoid tumors

MECHANISM OF ACTION

Evertor 10mg is a prohibition of mammalian target of rapamycin (mTOR), a serine-threonine kinase. Evertor bind with intercellular protein (FKBP-12), leads to inhibitory complex formation with mTOR complex 1 (mTORC1) this leads to inhibition of mTOR kinase activity.
Evertor decreased the effect of S6 ribosomal protein kinase (S6K1) and eukaryotic elongation factor 4E binding protein (4E-BP1) which are essential for protein synthesis. mTOR inhibited by Evertor lead to reduce cell multiplication and angiogenesis.

DOSAGE AND ADMINISTRATION OF EVERTOR

The recommended dose of the Tablet Evertor is 10mg should be taken as a single dose in all carcinogenic condition, except organ transplantation.

Organ transplant:
0.75mg orally twice daily.

Brain/intracranial tumor:
4.5mg/m2 orally once a day (for both pediatric and adult dose)

Hepatic impairment:
dose reduced to 7.5mg once daily followed by 5mg as a single dose. Evertor is in tablet form. It should be administered orally at the same time every day. Evertor should be taken with or without food. Evertor tablets should not crush or broken.

EVERTOR SIDE EFFECTS

The side effects of Evertor tablets are predicted by the terms of their onset, duration, and severity Side effects of Evertor is preventable and it is minimized Mouth sores, Mucositis, Stomatitis or esophagitis, Infection, Rash, itching or dry skin, Fatigue, Diarrhea, Edema, Stomach pain, Nausea, vomiting, Fever, Weakness or asthenia, Headache

STORAGE

Evertor 10mg should be stored in room temperature Keep away from moisture, heat, and light

MISSED DOSE

In case of the missed dose, patients must consult with the medical practitioner and follow the instructions given by them. On the other hand, the missed dose should be avoided and follow the regular dosing schedule.

FOR MORE INFORMATION:

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+91-97890 77748

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