OPDYTA 100MG
Opdyta 100mg belongs to a group of cancer drugs known as monoclonal antibodies. Opdyta 100mg is also known as an immune checkpoint inhibitor. Sometimes these drugs are called targeted therapies because they target specific proteins (receptors) on the surface of cells. Opdyta 100mg is a prescription drug which is used under the supervision of a doctor.INDICATION
Opdyta 100mg is indicated for the treatment of patients having Melanoma. Opdyta 100mg is indicated for the treatment of patients having Non-Small Cell Lung Cancer. Opdyta 100mg is indicated for the treatment of patients having Kidney (Renal Cell) Cancer.MECHANISM OF ACTION
Opdyta prohibits the molecule activity called PD-1, and it is a protein which prevents T cells from recognizing and attacking inflamed tissues and cancer cells. PD-1 can deceit the immune system into overlooking melanoma cells as normal cells.DOSAGE AND ADMINISTRATION
Opdyta recommended dosage for unresectable or metastatic melanoma :As a single agent is either 240mg every 2 weeks or 480mg every 4 weeks given as IV infusion over 30 minutes until disease progression or unacceptable toxicity
With ipilimumab. The recommended dose of Opdyta is 1mg/kg administrated as an intravenous infusion over 30 minutes, followed by ipilimumab 3mg/kg given as IV over 90 minutes on the same day. Duration 3 weeks of max 4 doses, after completing combination dose continue the single agent treatment.
COMMON SIDE EFFECTS
• Fatigue• Lymphocytopenia (Low White Blood Cells)
• Low Sodium
• Shortness of breath
• Musculoskeletal Pain
• Decreased Appetite
• Cough
PRECAUTIONS
Immune-mediated pneumonitis may appear to the patients; withhold for moderate and permanently discontinue for serious or life-threatening pneumonitisOther clinically significant and possible fatal immune-mediated side effects (eg, myocarditis, rhabdomyolysis, myositis, uveitis, iritis, pancreatitis) can appear after therapy discontinuation.
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